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Deleted in Azoospermia 2 (DAZ2) Peptide

DAZ2 适用: 人 宿主: 合成 BP, IHC, WB
产品编号 ABIN975594
发货至: 中国
  • 抗原 See all DAZ2 products
    DAZ2 (Deleted in Azoospermia 2 (DAZ2))
    宿主
    资源
    • 1
    合成
    应用范围
    Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-DAZ2 antibody (Catalog #: ARP40250_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    DAZ2 (Deleted in Azoospermia 2 (DAZ2))
    别名
    pDP1678 Peptide, DAZ2 Peptide, deleted in azoospermia 2 Peptide, deleted in azoospermia protein 2 Peptide, DAZ2 Peptide, LOC738583 Peptide
    背景
    DAZ2 is a member of the DAZ family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). This RNA-binding protein is important for spermatogenesis.This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications, one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat, the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified, this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat. Alternative splicing results in multiple transcript variants encoding different isoforms.

    Alias Symbols: pDP1678

    Protein Interaction Partner: PUM2

    Protein Size: 534
    分子量
    59 kDa
    基因ID
    57055
    NCBI登录号
    NM_001005785, NP_001005785
    UniProt
    Q2KHN6
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