CTDSP2 (CTD (Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 2) (Middle Region) Peptide
适用: 人
宿主: 合成
BP, WB
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- 抗原
- CTDSP2 (CTD (Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 2)
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- ASYIFHPENA VPVQSWFDDM ADTELLNLIP IFEELSGAED VYTSLGQLRA
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-CTDSP2 Antibody(ARP52097_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- CTDSP2 (CTD (Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 2)
- 物质类
- Peptide
- 背景
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CTDSP2 preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A.CTDSP2 negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. CTDSP2 is recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.CTDSP2 may contribute to the development of sarcomas.
Alias Symbols: OS4, PSR2, SCP2
Protein Interaction Partner: AR,POLR2A,SNAI1
Protein Size: 271 - 分子量
- 31 kDa
- 基因ID
- 10106
- NCBI登录号
- NM_005730, NP_005721
- UniProt
- O14595
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