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Collagen, Type IV, alpha 3 (COL4A3) (Middle Region) Peptide

COL4A3 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN975163
发货至: 中国
  • 抗原 See all COL4a3 (COL4A3) products
    COL4a3 (COL4A3) (Collagen, Type IV, alpha 3 (COL4A3))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 5
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    YRADDANVVR DRDLEVDTTL KSLSQQIENI RSPEGSRKNP ARTCRDLKMC
    产品特性
    This is a synthetic peptide designed for use in combination with anti-COL4A3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    COL4a3 (COL4A3) (Collagen, Type IV, alpha 3 (COL4A3))
    别名
    zTumstatin Peptide, [a]3(IV) Peptide, alpha3(IV) Peptide, collagen type IV alpha 3 chain Peptide, collagen, type IV, alpha 3 Peptide, COL4A3 Peptide, col4a3 Peptide, Col4a3 Peptide
    背景
    This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

    Alias Symbols: -

    Protein Interaction Partner: CAPN1,BGN,BMP1,CAPN1,CD36,CD44,CD93,COL7A1,DCN,DDR2,FGF7,FN1,HTRA1,IGFBP3,ITGA2,ITGA5,MATN2,MMP2,MMP9,NID1,P4HB,PAK1,PDGFB,PRELP,SPARC,TGFBI,THBS1,TMPRSS6,TXN,VWF,COL7A1,IGFBP3,ITGA2,ITGB1,MAG,MATN2,MMP2,NID1,NID2,Nid1,PKD1,PRELP,SPARC,THBS1,TXN,VWF

    Protein Size: 1464
    分子量
    137 kDa
    基因ID
    1285
    NCBI登录号
    NM_031362, NP_112730
    UniProt
    E7ENN2
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