CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (Middle Region) Peptide
CFLAR
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all FLIP (CFLAR) products
- FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-CFLAR antibody (Catalog #: AVARP02011_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
- 别名
- Clarp1 Peptide, cflar Peptide, CFLAR Peptide, FLIP Peptide, CASH Peptide, CASP8AP1 Peptide, CLARP Peptide, Casper Peptide, FLAME Peptide, FLAME-1 Peptide, FLAME1 Peptide, I-FLICE Peptide, MRIT Peptide, c-FLIP Peptide, c-FLIPL Peptide, c-FLIPR Peptide, c-FLIPS Peptide, 2310024N18Rik Peptide, A430105C05Rik Peptide, Cash Peptide, ENSMUSG00000072980 Peptide, Flip Peptide, Gm9845 Peptide, c-Flip Peptide, CASP8 and FADD-like apoptosis regulator a Peptide, CASP8 and FADD like apoptosis regulator Peptide, CASP8 and FADD like apoptosis regulator S homeolog Peptide, CASP8 and FADD-like apoptosis regulator Peptide, cflara Peptide, CFLAR Peptide, cflar Peptide, cflar.S Peptide, Cflar Peptide
- 背景
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CFLAR belongs to the peptidase C14A family. It is a apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. The protein acts as an inhibitor of TNFRSF6 mediated apoptosis. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. CFLAR lacks enzymatic (caspase) activity.
Alias Symbols: CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLIP, I-FLICE, MRIT, USURPIN, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS, FLAME1
Protein Interaction Partner: CASP3,CASP8,FADD,BCL2L1,CASP3,CASP8,DAXX,FADD,BCL2L1,CASP10,CASP2,CASP3,CASP6,CASP7,CASP8,DAXX,DEDD,DEDD2,FADD,IKBKB,MAP2K4,MAP2K7,NFKB1,PSEN2,RAF1,RIPK1,RIPK2,TNFRSF10B,TRAF1,TRAF2,BCL2L1,CASP10,CASP3,CASP8,CFLAR,DEDD,DEDD2,DOK2,FADD,FAS,ITCH,MAP3K14,NOD1,NOL3,RAF1,RIPK1,RIPK2,SF3B3,TNFRSF10A,TNFRSF10B,TP53,TRAF1,TRAF2,TRAF3,UBC
Protein Size: 480 - 分子量
- 55 kDa
- 基因ID
- 8837
- NCBI登录号
- NM_003879, NP_003870
- UniProt
- O15519
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