This is a synthetic peptide designed for use in combination with anti-CENPA antibody (Catalog #: ARP46041_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
浓度
1 mg/mL
缓冲液
Final peptide concentration is 1 mg/mL in PBS.
注意事项
Avoid repeated freeze-thaw cycles.
储存条件
-20 °C
储存方法
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
抗原
CENPA
(Centromere Protein A (CENPA))
别名
CENP-A Peptide, CenH3 Peptide, Cenp-A Peptide, cenpx Peptide, cenp-a Peptide, sim2 Peptide, Cenp-a Peptide, RGD1563607 Peptide, CENPA Peptide, centromere protein A Peptide, centromere protein-A Peptide, centromeric histone-3 like protein Peptide, centromere-specific histone H3 CENP-A Peptide, cenp-A Peptide, centromere protein A L homeolog Peptide, histone H3-like centromeric protein A Peptide, CENPA Peptide, Cenpa Peptide, CENP-A Peptide, cenpa Peptide, cenp-A Peptide, cnp1 Peptide, HAN_3g422 Peptide, Cenp-a Peptide, cenpa.L Peptide, CMU_016480 Peptide
背景
Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA is a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: CenH3, CENP-A
Protein Interaction Partner: DIAPH1,DIAPH2,AURKB,DIAPH1,DIAPH2,HIST1H3C,HIST1H4F,PARP1,PARP2,HIST1H3C,PARP1