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Centromere Protein A (CENPA) Peptide

CENPA 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN974833
发货至: 中国
  • 抗原 See all CENPA products
    CENPA (Centromere Protein A (CENPA))
    宿主
    资源
    • 3
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-CENPA antibody (Catalog #: ARP46041_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    CENPA (Centromere Protein A (CENPA))
    别名
    CENP-A Peptide, CenH3 Peptide, Cenp-A Peptide, cenpx Peptide, cenp-a Peptide, sim2 Peptide, Cenp-a Peptide, RGD1563607 Peptide, CENPA Peptide, centromere protein A Peptide, centromere protein-A Peptide, centromeric histone-3 like protein Peptide, centromere-specific histone H3 CENP-A Peptide, cenp-A Peptide, centromere protein A L homeolog Peptide, histone H3-like centromeric protein A Peptide, CENPA Peptide, Cenpa Peptide, CENP-A Peptide, cenpa Peptide, cenp-A Peptide, cnp1 Peptide, HAN_3g422 Peptide, Cenp-a Peptide, cenpa.L Peptide, CMU_016480 Peptide
    背景
    Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA is a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

    Alias Symbols: CenH3, CENP-A

    Protein Interaction Partner: DIAPH1,DIAPH2,AURKB,DIAPH1,DIAPH2,HIST1H3C,HIST1H4F,PARP1,PARP2,HIST1H3C,PARP1

    Protein Size: 140
    分子量
    16 kDa
    基因ID
    1058
    NCBI登录号
    NM_001809, NP_001800
    UniProt
    P49450
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