This is a synthetic peptide designed for use in combination with anti-Cdh1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.
Alias Symbols: AA960649, Ecad, L-CAM, MGC107495, UVO, Um
Protein Interaction Partner: Zeb1,Ctnnb1,Gna13,JUP,Ptprq