CBFA2T3
(Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
产品特性
This is a synthetic peptide designed for use in combination with anti-CBFA2T3 antibody (Catalog #: ARP33993_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
The t(16,21)(q24,q22) translocation is a rare but recurrent chromosomal abnormality associated with therapy-related myeloid malignancies. The translocation produces a chimeric gene made up of the 5'-region of the AML1 gene fused to the 3'-region of CBFA2T3. In addition, CBFA2T3 is a putative breast tumor suppressor.
Alias Symbols: ETO2, MTG16, MTGR2, ZMYND4
Protein Interaction Partner: CBFA2T2,CBFA2T3,HDAC1,HDAC3,PRKAR2A,RUNX1,RUNX1T1,CBFA2T2,HDAC1,HDAC2,HDAC3,HDAC6,HDAC8,LDB1,NCOR1,PRKAR2A,RUNX1T1,TAL1,TCF3