Calcium Modulating Ligand (CAMLG) (N-Term) Peptide
CAMLG
适用: 人
宿主: 合成
BP, WB
-
- 抗原 See all CAMLG products
- CAMLG (Calcium Modulating Ligand (CAMLG))
- 蛋白结构域
- N-Term
- 宿主
- 人
-
资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-CAMLG antibody (Catalog #: ARP48191_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
-
-
- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- 抗原
- CAMLG (Calcium Modulating Ligand (CAMLG))
- 别名
- MGC53900 Peptide, CAML Peptide, AI385748 Peptide, Camlg Peptide, Caml Peptide, calcium modulating ligand L homeolog Peptide, calcium modulating ligand Peptide, camlg.L Peptide, CAMLG Peptide, camlg Peptide, Caml Peptide, Camlg Peptide
- 背景
-
The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. CAMLG functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.
Alias Symbols: CAML, MGC163197
Protein Interaction Partner: IER3,EGFR,PKHD1,TNFRSF13B,EGFR,PPIB,TNFRSF13B
Protein Size: 296 - 分子量
- 33 kDa
- 基因ID
- 819
- NCBI登录号
- NM_001745, NP_001736
- UniProt
- P49069
-
You are here:
