This is a synthetic peptide designed for use in combination with anti-BCL2L1 antibody (Catalog #: AVARP02008_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
BCL2L1 encodes a protein which belongs to the BCL-2 protein family. The proteins encoded by BCL2L1 are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis.
Protein Interaction Partner: CRYAA,CRYAB,BAD,BAD,BAD,BAX,BAX,BAX,BBC3,BBC3,BBC3,BCL2L11,BCL2L11,BID,BID,BID,BID,BID,BIK,BIK,BMF,BMF,HRK,HRK,HRK,MOAP1,RTN1,RTN4,TP53,TPT1,ANTXR1,APAF1,AVEN,BAD,BAG1,BAK1,BAX,BBC3,BCAP31,BCL2,BCL2L1,BCL2L10,BCL2L11,BCL2L12,BCL2L14,BCLAF1,BECN1,BID,BIK,BMF,BNIP1,BNIP3,BNIP3L,CAPN1,CASP1,CASP8,CASP9,CFLAR,CRYAA,CRYAB,CYCS,FKBP8,HRK,IKZF3,IRS1,IRS2,MAPK8,MCL1,MOAP1,NLRP1,PMAIP1,PPP1CA,PSEN1,PSEN2,RAD9A,RTN1,RTN4,SIVA1,SNCA,SPNS1,TMBIM6,TP53,VDAC1,APAF1,AVEN,BAD,BAK1,BAX,BBC3,BCAP31,BCL2,BCL2L11,BCL2L14,BECN1,BID,BIK,BLK,BNIP1,BNIP3,BNIPL,Bcl2l11,CASP2,CASP8,CASP9,CFLAR,CFLAR,CYCS,DYNLL1,FKBP8,HRK,IKZF3,IRS1,MCL1,MOAP1,PGAM5,PMAIP1,PPP1CA,PSEN1,PSEN2,RAD9A,RAF1,RTN1,RTN4,SPNS1,VDAC1