BCL2-Associated Agonist of Cell Death (BAD) (C-Term) Peptide
BAD
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all BAD products
- BAD (BCL2-Associated Agonist of Cell Death (BAD))
- 蛋白结构域
- C-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-BAD antibody (Catalog #: ARP30325_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- BAD (BCL2-Associated Agonist of Cell Death (BAD))
- 别名
- bad Peptide, fa01b12 Peptide, wu:fa01b12 Peptide, wu:fa96d04 Peptide, BAD Peptide, BBC2 Peptide, BCL2L8 Peptide, AI325008 Peptide, Bbc2 Peptide, BCL2-associated agonist of cell death b Peptide, BCL2 associated agonist of cell death Peptide, BCL2-associated agonist of cell death Peptide, badb Peptide, BAD Peptide, Bad Peptide
- 背景
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BAD is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Alias Symbols: BBC2, BCL2L8
Protein Interaction Partner: BCL2,BCL2,BCL2,BCL2A1,BCL2L1,BCL2L1,BCL2L2,AKT1,BCL2,BCL2A1,BCL2L1,BCL2L10,BCL2L2,EWSR1,HRK,MAP2K5,MAPK8,MCL1,PAK1,PAK7,PIM1,PIM2,PIM3,PPP1CA,PPP3CA,PRKACA,RAF1,RPS6KA1,RPS6KA2,RPS6KA3,RPS6KA5,S100A10,SFN,SNCA,WASF1,YWHAB,YWHAE,YWHAG,YWHAH,YWHAQ,YWHAZ,AKT1,BCL2,BCL2A1,BCL2L1,BCL2L1,BCL2L2,EWSR1,MCL1,PIM2,PRKACA,PRKCI,RPS6KA1,RPS6KA5,S100A10,SFN,SNCA,YWHAB,YWHAE,YWHAH,YWHAQ,YWHAZ
Protein Size: 168 - 分子量
- 18 kDa
- 基因ID
- 572
- NCBI登录号
- NM_004322, NP_004313
- UniProt
- Q92934
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