This is a synthetic peptide designed for use in combination with anti-ASL antibody (Catalog #: ARP41666_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
浓度
1 mg/mL
缓冲液
Final peptide concentration is 1 mg/mL in PBS.
注意事项
Avoid repeated freeze-thaw cycles.
储存条件
-20 °C
储存方法
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
抗原
ASL
(Argininosuccinate Lyase (ASL))
别名
ASAL Peptide, 2510006M18Rik Peptide, zgc:63532 Peptide, BA4879 Peptide, PSPTO0125 Peptide, Adl Peptide, Asl Peptide, argininosuccinate lyase Peptide, argininosuccinate lyase ArgH Peptide, adenylosuccinate lyase Peptide, argininosuccinate lyase L homeolog Peptide, ASL Peptide, Asl Peptide, asl Peptide, argH2 Peptide, argH Peptide, arg7 Peptide, CNC04420 Peptide, STHERM_c13370 Peptide, Adsl Peptide, asl.L Peptide, ARG7 Peptide
背景
ASL is a member of the lyase 1 family. The protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in its gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency.This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described.