Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) (Middle Region) Peptide
ASCL1
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all ASCL1 products
- ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-ASCL1 antibody (Catalog #: AVARP00017_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
- 别名
- ASH1 Peptide, HASH1 Peptide, MASH1 Peptide, bHLHa46 Peptide, AI225900 Peptide, Mash1 Peptide, ASCL1 Peptide, Zash-1a Peptide, ash Peptide, asha Peptide, id:ibd5085 Peptide, im:7138587 Peptide, si:dkey-264k15.2 Peptide, zash1a Peptide, zasha Peptide, Xash1 Peptide, ascl1-A Peptide, Zash-1b Peptide, ashb Peptide, zashb Peptide, achaete-scute family bHLH transcription factor 1 Peptide, achaete-scute family bHLH transcription factor 1a Peptide, achaete-scute family bHLH transcription factor 1 L homeolog Peptide, achaete-scute complex homolog 1 Peptide, achaete-scute family bHLH transcription factor 1b Peptide, ASCL1 Peptide, Ascl1 Peptide, ascl1a Peptide, ascl1.L Peptide, LOC100220505 Peptide, ascl1b Peptide
- 背景
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ASCL1 may play a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. ASCL1 is essential for the generation of olfactory and autonomic neurons. ASCL1 activates transcription by binding to the E box (5'-CANNTG-3').This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ASH1, HASH1, MASH1, bHLHa46
Protein Interaction Partner: ASCL1,BMP2,EP300,MEF2A,NEUROG2,TCF4,UBQLN1,EP300,MEF2A,TCF4
Protein Size: 236 - 分子量
- 25 kDa
- 基因ID
- 429
- NCBI登录号
- NM_004316, NP_004307
- UniProt
- P50553
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