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Aryl-Hydrocarbon Receptor Repressor (AHRR) (Middle Region) Peptide

AHRR 适用: 小鼠 宿主: 合成 BP, WB
产品编号 ABIN973020
发货至: 中国
  • 抗原 See all AHRR products
    AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))
    蛋白结构域
    Middle Region
    宿主
    小鼠
    资源
    • 1
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    CLRGGPDLLD PKGTSGDREE EDQKHILRRS PGAWGQREMH KYSYGLETPV
    产品特性
    This is a synthetic peptide designed for use in combination with anti-Ahrr Antibody(ARP37012_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))
    别名
    mKIAA1234 Peptide, AHH Peptide, AHHR Peptide, bHLHe77 Peptide, ahh Peptide, ahhr Peptide, bhlhe77 Peptide, ahrr2 Peptide, aryl-hydrocarbon receptor repressor Peptide, aryl hydrocarbon receptor repressor-like Peptide, uncharacterized LOC723045 Peptide, aryl-hydrocarbon receptor repressor L homeolog Peptide, aryl hydrocarbon receptor repressor Peptide, aryl-hydrocarbon receptor repressor b Peptide, Ahrr Peptide, AHRR Peptide, LOC529500 Peptide, LOC723045 Peptide, ahrr.L Peptide, LOC100455869 Peptide, ahrr Peptide, LOC100136487 Peptide, ahrrb Peptide
    背景
    Ahrr mediates dioxin toxicity and is involved in regulation of cell growth and differentiation. Ahrr represses the transcription activity of AHR by competing with this transcription factor for heterodimer formation with the ARNT and subsequently binding to the xenobiotic response element (XRE) sequence present in the promoter regulatory region of variety of genes. Ahrr represses CYP1A1 by binding the XRE sequence and recruiting ANKRA2, HDAC4 and/or HDAC5. Autoregulates its expression by associating with its own XRE site.

    Alias Symbols: KIAA1234, mKIAA1234

    Protein Size: 701
    分子量
    78 kDa
    基因ID
    11624
    NCBI登录号
    NM_009644, NP_033774
    UniProt
    Q3U1U7
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