ACVRL1
(Activin A Receptor Type II-Like 1 (ACVRL1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
产品特性
This is a synthetic peptide designed for use in combination with anti-ACVRL1 antibody (Catalog #: ARP44199_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
浓度
1 mg/mL
缓冲液
Final peptide concentration is 1 mg/mL in PBS.
注意事项
Avoid repeated freeze-thaw cycles.
储存条件
-20 °C
储存方法
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
抗原
ACVRL1
(Activin A Receptor Type II-Like 1 (ACVRL1))
别名
ACVRL1 Peptide, vgb Peptide, alk1 Peptide, zehn1109 Peptide, hm:zehn1109 Peptide, ACVRLK1 Peptide, ALK-1 Peptide, ALK1 Peptide, HHT Peptide, HHT2 Peptide, ORW2 Peptide, SKR3 Peptide, TSR-I Peptide, R-3 Peptide, R3 Peptide, SETHKIR Peptide, AI115505 Peptide, AI427544 Peptide, Acvrlk1 Peptide, Alk1 Peptide, activin A receptor like type 1 Peptide, activin A receptor type II-like 1 Peptide, activin A receptor, type II-like 1 Peptide, ACVRL1 Peptide, acvrl1 Peptide, Acvrl1 Peptide
背景
ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. ACVRL1, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
Alias Symbols: ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I
Protein Interaction Partner: XIAP,ACVR2A,SNX6,TGFB1,TGFB3,TGFBR1,TGFBR2,TGFBRAP1,XIAP,SNX6,TGFB1