Apoptosis Antagonizing Transcription Factor (AATF) Peptide
AATF
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all AATF products
- AATF (Apoptosis Antagonizing Transcription Factor (AATF))
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-AATF antibody (Catalog #: ARP38957_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- AATF (Apoptosis Antagonizing Transcription Factor (AATF))
- 别名
- AATF Peptide, ded Peptide, che1 Peptide, che-1 Peptide, cb109 Peptide, sb:cb109 Peptide, wu:fc13d05 Peptide, zgc:162071 Peptide, CHE-1 Peptide, CHE1 Peptide, DED Peptide, 4933415H02Rik Peptide, 5830465M17Rik Peptide, Che-1 Peptide, Trb Peptide, Ded Peptide, apoptosis antagonizing transcription factor Peptide, Apoptosis antagonizing transcription factor Peptide, apoptosis antagonizing transcription factor S homeolog Peptide, AATF Peptide, aatf Peptide, BFR2 Peptide, NAEGRDRAFT_56916 Peptide, Aatf Peptide, aatf.S Peptide
- 背景
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The AATF is a protein that was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. AATF contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of AATF interfered with MAP3K12 induced apoptosis.The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis.
Alias Symbols: DED, CHE1, CHE-1
Protein Interaction Partner: POLR2J,RB1,ATM,ATR,CHEK1,CHEK2,DAPK3,DAZAP2,LDOC1,MAPT,MPHOSPH6,MPP6,PAWR,POLR2J,RB1,RELA,SP1,TSG101,DAZAP2,LDOC1,MAPT,MPP6,PAWR,POLR2J,RB1,RBL1,RBL2,SP1,Tsg101
Protein Size: 560 - 分子量
- 63 kDa
- 基因ID
- 26574
- NCBI登录号
- NM_012138, NP_036270
- UniProt
- Q9NY61
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