Protein Arginine Methyltransferase 2 (PRMT2) Peptide
PRMT2
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
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- 抗原 See all PRMT2 products
- PRMT2 (Protein Arginine Methyltransferase 2 (PRMT2))
- 蛋白类型
- Synthetic
- 宿主
- 哺乳动物
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- ESQGEEPAEC SEAGLLQEGV QPEEFVAIAD YAATDETQLS FLRGEKILIL
- 产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of PRMT2 antibody,
Alternative Names: PRMT2 control peptide, PRMT2 antibody Blocking Peptide, Anti-PRMT2 Blocking Peptide, Protein Arginine Methyltransferase 2 Blocking Peptide, PRMT2, PRMT-2, PRMT 2, PRMT-2 Blocking Peptide, PRMT 2 Blocking Peptide
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- 应用备注
- Optimal conditions should be determined by the investigator
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- 缓冲液
- PBS
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C long term.
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- 抗原
- PRMT2 (Protein Arginine Methyltransferase 2 (PRMT2))
- 别名
- PRMT2 Peptide, DKFZp459N1919 Peptide, HRMT1L1 Peptide, Hrmt1l1 Peptide, AI504737 Peptide, protein arginine methyltransferase 2 Peptide, protein arginine methyltransferase 2 L homeolog Peptide, protein arginine N-methyltransferase 2 Peptide, PRMT2 Peptide, Prmt2 Peptide, prmt2.L Peptide
- 背景
- The protein arginine methyltransferases (PRMTs) include a family of proteins with related putative methyltransferase domains that modify chromatin and regulate cellular transcription. PRMT2 inhibits NF-kappaB-dependent transcription and promotes apoptosis and it exerts this effect by blocking nuclear export of IkappaB-alpha through a leptomycin-sensitive pathway, increasing nuclear IkappaB-alpha and decreasing NF-kappaB DNA binding. PRMT2 also rendered cells susceptible to apoptosis by cytokines or cytotoxic drugs, likely due to its effects on NF-kappaB.
- 分子量
- 48 kDa
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