A synthetic peptide for use as a blocking control in assays to test for specificity of NDST4 antibody, Alternative Names: NDST4 control peptide, NDST4 antibody Blocking Peptide, Anti-NDST4 Blocking Peptide, N-Deacetylase/N-Sulfotransferase Blocking Peptide, Heparan Glucosaminyl 4 Blocking Peptide, NDST4, NDST-4, NDST 4, NDST-4 Blocking Peptide, NDST 4 Blocking Peptide
纯化方法
The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
NDST4 is an essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. It modifies the GlcNAc-GlcA dissacharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. NDST4 has low deacetylase activity but high sulfotransferase activity.