A synthetic peptide for use as a blocking control in assays to test for specificity of CERKL antibody, Alternative Names: CERKL control peptide, CERKL antibody Blocking Peptide, Anti-CERKL Blocking Peptide, ceramide kinase-like Blocking Peptide, RP26 Blocking Peptide
This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.