Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) (Middle Region) Peptide
PMAIP1
适用: 小鼠
宿主: 合成
BP, WB
-
- 抗原 See all NOXA (PMAIP1) products
- NOXA (PMAIP1) (Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))
- 蛋白结构域
- Middle Region
- 宿主
- 小鼠
-
资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- TWSAPDITVV LAQMPGKSQK SRMRSPSPTR VPADLKDECA QLRRIGDKVN
- 产品特性
- This is a synthetic peptide designed for use in combination with anti- PMAIP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- 抗原
- NOXA (PMAIP1) (Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))
- 别名
- TN3 Peptide, PMAIP1 Peptide, zgc:162379 Peptide, APR Peptide, NOXA Peptide, Noxa Peptide, phorbol-12-myristate-13-acetate-induced protein 1 Peptide, PMAIP1 Peptide, pmaip1 Peptide, Pmaip1 Peptide
- 背景
-
Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1 (By similarity). Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1.
Alias Symbols: Noxa
Protein Size: 103 - 基因ID
- 58801
- NCBI登录号
- NM_021451, NP_067426
- UniProt
- Q9JM54
-
You are here:
