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Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA) (Middle Region) Peptide

PIGA 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN5513922
发货至: 中国
  • 抗原 See all PIGA products
    PIGA (Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 3
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    IICVSYTSKE NTVLRAALNP EIVSVIPNAV DPTDFTPDPF RRHDSITIVV
    产品特性
    This is a synthetic peptide designed for use in combination with anti-PIGA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    PIGA (Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA))
    别名
    GPI3 Peptide, MCAHS2 Peptide, PIG-A Peptide, AI194334 Peptide, Pig-a Peptide, im:6911675 Peptide, zgc:56589 Peptide, phosphatidylinositol glycan anchor biosynthesis class A Peptide, phosphatidylinositol glycan anchor biosynthesis, class A Peptide, PIGA Peptide, Piga Peptide, piga Peptide
    背景
    This gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been characterized. A related pseudogene is located on chromosome 12.

    Alias Symbols: GPI3, PNH1, PIG-A, MCAHS2

    Protein Size: 484
    基因ID
    5277
    NCBI登录号
    NM_002641, NP_002632
    UniProt
    P37287
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