This is a synthetic peptide designed for use in combination with anti- PPP2R1B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
储存条件
-20 °C
储存方法
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
抗原
PPP2R1B
(Protein Phosphatase 2, Regulatory Subunit A, beta (PPP2R1B))
别名
2410091N08Rik Peptide, AI790395 Peptide, PP2A-Abeta Peptide, PR65B Peptide, protein phosphatase 2, regulatory subunit A, beta Peptide, protein phosphatase 2 scaffold subunit Abeta Peptide, protein phosphatase 2 scaffold subunit A beta Peptide, protein phosphatase 2 regulatory subunit A, beta S homeolog Peptide, Ppp2r1b Peptide, PPP2R1B Peptide, ppp2r1b.S Peptide
背景
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described.