Inositol Polyphosphate-5-Phosphatase, 72 KDa (INPP5E) (Middle Region) Peptide
INPP5E
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all INPP5E products
- INPP5E (Inositol Polyphosphate-5-Phosphatase, 72 KDa (INPP5E))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- SLQEIPKSRG VLSSERGSPS SGGNPLSGVA SSSPNLPHRD AAVAGSSPRL
- 产品特性
- This is a synthetic peptide designed for use in combination with anti- INPP5E Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- INPP5E (Inositol Polyphosphate-5-Phosphatase, 72 KDa (INPP5E))
- 别名
- 1200002L24Rik Peptide, 72kDa Peptide, mKIAA0123 Peptide, CORS1 Peptide, CPD4 Peptide, JBTS1 Peptide, MORMS Peptide, PPI5PIV Peptide, PMPCA Peptide, inositol polyphosphate-5-phosphatase E Peptide, Inpp5e Peptide, INPP5E Peptide
- 背景
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The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. Studies of the mouse counterpart suggest that this protein may hydrolyze phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,5-bisphosphate on the cytoplasmic Golgi membrane and thereby regulate Golgi-vesicular trafficking. Mutations in this gene cause Joubert syndrome, a clinically and genetically heterogenous group of disorders characterized by midbrain-hindbrain malformation and various associated ciliopathies that include retinal dystrophy, nephronophthisis, liver fibrosis and polydactyly. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: CPD4, CORS1, JBTS1, MORMS, PPI5PIV
Protein Size: 610 - 基因ID
- 56623
- NCBI登录号
- NM_019892, NP_063945
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