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Eyes Absent Homolog 4 (EYA4) (Middle Region) Peptide

EYA4 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN5512992
发货至: 中国
  • 抗原 See all EYA4 products
    EYA4 (Eyes Absent Homolog 4 (EYA4))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 6
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    QESLPGLTNQ PGEFDTMQSP STPIKDLDER TCRSSGSKSR GRGRKNNPSP
    产品特性
    This is a synthetic peptide designed for use in combination with anti- EYA4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    EYA4 (Eyes Absent Homolog 4 (EYA4))
    别名
    B130023L16Rik Peptide, CMD1J Peptide, DFNA10 Peptide, EYA transcriptional coactivator and phosphatase 4 Peptide, Eya4 Peptide, EYA4 Peptide
    背景
    This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator through its protein phosphatase activity, and it may be important for eye development, and for continued function of the mature organ of Corti. Mutations in this gene are associated with postlingual, progressive, autosomal dominant hearing loss at the deafness, autosomal dominant non-syndromic sensorineural 10 locus. The encoded protein is also a putative oncogene that mediates DNA repair, apoptosis, and innate immunity following DNA damage, cellular damage, and viral attack. Defects in this gene are also associated with dilated cardiomyopathy 1J. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

    Alias Symbols: CMD1J, DFNA10

    Protein Size: 585
    基因ID
    2070
    NCBI登录号
    NM_001301012, NP_004091
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