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Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10) (N-Term) Peptide

CHRNA10 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN5512918
发货至: 中国
  • 抗原 See all CHRNA10 products
    CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))
    蛋白结构域
    N-Term
    宿主
    资源
    • 1
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    GGLDAIRIPS SLVWRPDIVL YNKADAQPPG SASTNVVLRH DGAVRWDAPA
    产品特性
    This is a synthetic peptide designed for use in combination with anti-CHRNA10 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))
    别名
    si:dkey-24p1.3 Peptide, ALPHA 10 nAChR Peptide, cholinergic receptor, nicotinic, alpha polypeptide 10 Peptide, cholinergic receptor nicotinic alpha 10 subunit Peptide, cholinergic receptor, nicotinic, alpha 10a Peptide, neuronal acetylcholine receptor subunit alpha-10 Peptide, cholinergic receptor, nicotinic, alpha 10 (neuronal) Peptide, Chrna10 Peptide, CHRNA10 Peptide, chrna10a Peptide, LOC100344381 Peptide
    背景
    CHRNA10 is an ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.

    Alias Symbols: CHRNA10,NACHRA10,

    Protein Size: 450
    基因ID
    57053
    NCBI登录号
    NP_065135
    UniProt
    Q9GZZ6
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