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Integrin alpha M (ITGAM) (C-Term) Peptide

ITGAM 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN5512204
发货至: 中国
  • 抗原 See all CD11b (ITGAM) products
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    蛋白结构域
    C-Term
    宿主
    资源
    • 3
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    PFEVPNPLPL IVGSSVGGLL LLALITAALY KLGFFKRQYK DMMSEGGPPG
    产品特性
    This is a synthetic peptide designed for use in combination with anti-ITGAM Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    别名
    CD11b/CD18 Peptide, CR3 Peptide, CR3A Peptide, Cd11b Peptide, F730045J24Rik Peptide, Ly-40 Peptide, MAC1 Peptide, Mac-1 Peptide, Mac-1a Peptide, CD11B Peptide, MAC-1 Peptide, MAC1A Peptide, MO1A Peptide, SLEB6 Peptide, C3bi Peptide, integrin subunit alpha M Peptide, integrin alpha M Peptide, integrin, alpha M (complement component 3 receptor 3 subunit) Peptide, integrin alpha-M Peptide, ITGAM Peptide, Itgam Peptide, LOC100351865 Peptide
    背景
    This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: CR3A, MO1A, CD11B, MAC-1, MAC1A, SLEB6

    Protein Size: 1152
    基因ID
    3684
    NCBI登录号
    NM_000632, NP_000623
    UniProt
    P11215
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