This is a synthetic peptide designed for use in combination with anti-ACCN4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
ACCN4 Peptide, BNAC4 Peptide, Accn4 Peptide, Spasic Peptide, acid sensing ion channel subunit family member 4 S homeolog Peptide, acid sensing ion channel subunit family member 4 Peptide, acid-sensing (proton-gated) ion channel family member 4 Peptide, asic4.S Peptide, ASIC4 Peptide, Asic4 Peptide
背景
This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC.