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Chromosome 10 Open Reading Frame 2 (C10ORF2) (C-Term) Peptide

C10ORF2 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN5511854
发货至: 中国
  • 抗原 See all C10orf2 (C10ORF2) products
    C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))
    蛋白结构域
    C-Term
    宿主
    资源
    • 3
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    FRKFATDNNC HVTLVIHPRK EDDDKELQTA SIFGSAKASQ EADNVLILQD
    产品特性
    This is a synthetic peptide designed for use in combination with anti-PEO1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))
    别名
    ATXN8 Peptide, IOSCA Peptide, MTDPS7 Peptide, PEO Peptide, PEO1 Peptide, PEOA3 Peptide, SANDO Peptide, SCA8 Peptide, TWINL Peptide, C6H10orf2 Peptide, D19Ertd626e Peptide, Twinl Peptide, twinkle mtDNA helicase L homeolog Peptide, twinkle mtDNA helicase Peptide, twnk.L Peptide, TWNK Peptide, Twnk Peptide
    背景
    This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

    Alias Symbols: PEO1,C10orf2,

    Protein Size: 684
    基因ID
    56652
    NCBI登录号
    NP_068602
    UniProt
    Q96RR1
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