(1 reference)-
- 抗原
- G3-C12
-
- 限制
- 仅限研究用
-
- 储存条件
- -20 °C
-
-
: "Inhibition of metastatic tumor formation in vivo by a bacteriophage display-derived galectin-3 targeting peptide." in: Clinical & experimental metastasis, Vol. 30, Issue 2, pp. 119-32, (2013) (PubMed).
-
: "Inhibition of metastatic tumor formation in vivo by a bacteriophage display-derived galectin-3 targeting peptide." in: Clinical & experimental metastasis, Vol. 30, Issue 2, pp. 119-32, (2013) (PubMed).
-
- 抗原
- G3-C12
- 背景
- Galectin-3 is a member of the galectin family of beta-galactoside-binding animal lectins. Galectin-3 is overexpressed in a wide range of neoplasms and is associated with tumor growth and metastases. Given this fact, radiolabeled galectin-3-targeting molecules may be useful for the noninvasive imaging of tumors expressing galectin-3, as well as for targeted radionuclide therapy. In this study, the tumor cell-targeting and SPECT properties of a galectin-3-avid peptide identified from bacteriophage display were evaluated in human breast carcinoma cells and in human breast tumor-bearing mice. The galectin-3-avid peptide G3-C12 (ANTPCGPYTHDCPVKR) was synthesized with a Gly-Ser-Gly (GSG) linker at the amino terminus.
-
You are here:
