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Corticotropin-Like Intermediate Peptide (CLIP) (AA 86-100) Peptide

CLIP
产品编号 ABIN399362
发货至: 中国
  • 抗原 See all CLIP products
    CLIP (Corticotropin-Like Intermediate Peptide (CLIP))
    蛋白结构域
    AA 86-100
    序列
    PVSKMRMATP LLMQA
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    储存条件
    -20°C
  • Chen, Li, Depontieu, McMiller, English, Shabanowitz, Kos, Sidney, Sette, Rosenberg, Hunt, Mariuzza, Topalian: "Structure-based design of altered MHC class II-restricted peptide ligands with heterogeneous immunogenicity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 10, pp. 5097-106, (2013) (PubMed).

  • 抗原
    CLIP (Corticotropin-Like Intermediate Peptide (CLIP))
    背景
    This is amino acids 86 to 100 fragment of class II-associated invariant chain peptide called CLIP. The major histocompatibility complex class II molecule displays peptide fragments of foreign proteins to trigger a defensive reaction from the immune system. Before insertion of the foreign peptides into the binding groove, a place-holding peptide CLIP is removed. This is accomplished by the molecule DM, which is shown to increase the dissociation rate of a CLIP peptide from class II.
    分子量
    1674.100
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