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Ring Finger Protein 216 (RNF216) (N-Term) Peptide

RNF216 适用: 人, 小鼠 宿主: 合成 BP, WB
产品编号 ABIN2185638
发货至: 中国
  • 抗原 See all RNF216 products
    RNF216 (Ring Finger Protein 216 (RNF216))
    蛋白结构域
    N-Term
    宿主
    人, 小鼠
    资源
    • 1
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    IVNPRLEQKV IILGENGLLF PESEPLEVQN QSSEDSETEL LSNPGEPAAS
    产品特性
    This is a synthetic peptide designed for use in combination with anti-Rnf216 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeat freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    RNF216 (Ring Finger Protein 216 (RNF216))
    别名
    RGD1565135 Peptide, TRIAD3 Peptide, RNF216 Peptide, zin Peptide, u7i1 Peptide, triad3 Peptide, ubce7ip1 Peptide, MGC147026 Peptide, 2810055g22rik Peptide, 2810055G22Rik Peptide, AI647468 Peptide, AU019462 Peptide, C86502 Peptide, F830018F18Rik Peptide, UIP83 Peptide, Ubce7ip1 Peptide, CAHH Peptide, U7I1 Peptide, UBCE7IP1 Peptide, ZIN Peptide, ring finger protein 216 Peptide, Rnf216 Peptide, RNF216 Peptide, rnf216 Peptide
    背景
    Rnf216 acts as an E3 ubiquitin ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. It promotes degradation of TRAF3, TLR4 and TLR9. It contributes to the regulation of antiviral responses. It down-regulates activation of NF-kappa-B, IRF3 activation and IFNB production and promotes TNF and RIP mediated apoptosis.

    Protein Size: 853
    分子量
    93 kDa
    基因ID
    108086
    UniProt
    P58283
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