Interleukin 4 Receptor (IL4R) (C-Term) Peptide
IL4R
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all IL4 Receptor (IL4R) products
- IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
- 蛋白结构域
- C-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- GLDREPPRSP QSSHLPSSSP EHLGLEPGEK VEDMPKPPLP QEQATDPLVD
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-IL4R Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeat freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
- 别名
- IL4R Peptide, il-4ra Peptide, zgc:113063 Peptide, CD124 Peptide, IL-4RA Peptide, IL4RA Peptide, Il4ra Peptide, IL4 Peptide, Il4r Peptide, interleukin 4 receptor Peptide, interleukin 4 receptor, tandem duplicate 1 Peptide, interleukin 4 receptor, alpha Peptide, IL4R Peptide, il4r.1 Peptide, Il4r Peptide, Il4ra Peptide
- 背景
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This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.
Protein Size: 825 - 分子量
- 87 kDa
- 基因ID
- 3566
- UniProt
- P24394
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