Ephrin B3 (EFNB3) (C-Term) Peptide
EFNB3
适用: 人, 小鼠
宿主: 合成
BP, WB
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- 抗原 See all Ephrin B3 (EFNB3) products
- Ephrin B3 (EFNB3)
- 蛋白结构域
- C-Term
- 宿主
- 人, 小鼠
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- AGAGGAMCWR RRRAKPSESR HPGPGSFGRG GSLGLGGGGG MGPREAEPGE
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-Efnb3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeat freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- Ephrin B3 (EFNB3)
- 别名
- efnb3-A Peptide, EphB3 Peptide, EFNB3 Peptide, efnb3 Peptide, id:ibd5049 Peptide, zgc:111938 Peptide, EFL-6 Peptide, ELF-3 Peptide, Elk-L3 Peptide, Epl8 Peptide, LERK-8 Peptide, NLERK-2 Peptide, ELK-L3 Peptide, RGD1565678 Peptide, EFL6 Peptide, EPLG8 Peptide, LERK8 Peptide, ephrin B3 Peptide, ephrin-B3 L homeolog Peptide, ephrin-B3b Peptide, ephrin-B3 Peptide, EFNB3 Peptide, efnb3.L Peptide, efnb3b Peptide, efnb3 Peptide, Efnb3 Peptide
- 背景
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Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Efnb3 binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. It may play a pivotal role in forebrain function. It binds to, and induce the collapse of, commissural axons/growth cones in vitro. Efnb3 may play a role in constraining the orientation of longitudinally projecting axons.
Alias Symbols: EFL-6, ELF-3, Elk-L3, Epl8, LERK-8, NLERK-2
Protein Size: 340 - 分子量
- 36 kDa
- 基因ID
- 13643
- NCBI登录号
- NM_007911, NP_031937
- UniProt
- O35393
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