TIMP Metallopeptidase Inhibitor 1 (TIMP1) (N-Term) Peptide
TIMP1
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all TIMP1 products
- TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
- 蛋白结构域
- N-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- QRYEIKMTKM YKGFQALGDA ADIRFVYTPA MESVCGYFHR SHNRSEEFLI
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-TIMP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeat freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
- 别名
- TIMP-1 Peptide, TIMP1 Peptide, DKFZp468A0912 Peptide, CLGI Peptide, EPA Peptide, EPO Peptide, HCI Peptide, TIMP Peptide, Timp Peptide, Clgi Peptide, TIMP metallopeptidase inhibitor 1 Peptide, tissue inhibitor of metalloproteinase 1 Peptide, TIMP1 Peptide, Timp1 Peptide
- 背景
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This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.
Alias Symbols: CLGI, EPA, HCI, TIMP
Protein Size: 207 - 分子量
- 22 kDa
- 基因ID
- 7076
- NCBI登录号
- NM_003254, NP_003245
- UniProt
- Q6FGX5
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