This is a synthetic peptide designed for use in combination with anti-GABRB3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
浓度
1 mg/mL
缓冲液
Final peptide concentration is 1 mg/mL in PBS.
注意事项
Avoid repeat freeze-thaw cycles.
储存条件
-20 °C
储存方法
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
抗原
GABRB3
(gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))
别名
GABRB3 Peptide, eca5 Peptide, LOC100230475 Peptide, ECA5 Peptide, A230092K12Rik Peptide, AW049585 Peptide, Cp1 Peptide, Gabrb-3 Peptide, beta3 Peptide, gamma-aminobutyric acid type A receptor beta3 subunit Peptide, gamma-aminobutyric acid (GABA) A receptor, beta 3 Peptide, gamma-aminobutyric acid type A receptor beta 3 subunit Peptide, gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 Peptide, GABRB3 Peptide, gabrb3 Peptide, Gabrb3 Peptide
背景
This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one the subunits of a multi-subunit chloride channel that serves as the receptor for gamma-aminobutyric acid, a major inhibitory neurotransmitter of the mammalian nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two other genes encoding related subunits of the family. This gene may be associated with the pathogenesis of several disorders including Angelman syndrome, Prader-Willi syndrome, nonsyndromic orofacial clefts, epilepsy and autism. Alternatively spliced transcript variants encoding distinct isoforms have been described.