Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (Middle Region) Peptide
KCNJ11
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all KCNJ11 products
- KCNJ11 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- SMIISATIHM QVVRKTTSPE GEVVPLHQVD IPMENGVGGN SIFLVAPLII
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-KCNJ11 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeat freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- KCNJ11 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))
- 别名
- kir6.2 Peptide, Kir6.2 Peptide, mBIR Peptide, BIR Peptide, HHF2 Peptide, IKATP Peptide, KIR6.2 Peptide, PHHI Peptide, TNDM3 Peptide, potassium voltage-gated channel subfamily J member 11 Peptide, potassium inwardly-rectifying channel, subfamily J, member 11 Peptide, potassium inwardly rectifying channel, subfamily J, member 11 Peptide, KCNJ11 Peptide, kcnj11 Peptide, Kcnj11 Peptide
- 背景
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Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM).
Alias Symbols: BIR, HHF2, IKATP, KIR6.2, PHHI, TNDM3
Protein Size: 303 - 分子量
- 33 kDa
- 基因ID
- 3767
- NCBI登录号
- NM_001166290, NP_001159762
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