Myb-Like, SWIRM and MPN Domains 1 (MYSM1) (C-Term) Peptide
MYSM1
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all MYSM1 products
- MYSM1 (Myb-Like, SWIRM and MPN Domains 1 (MYSM1))
- 蛋白结构域
- C-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- CLQKLLECMR KTLSKVTNCF MAEEFLTEIE NLFLSNYKSN QENGVTEENC
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-MYSM1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- MYSM1 (Myb-Like, SWIRM and MPN Domains 1 (MYSM1))
- 别名
- 2A-DUB Peptide, 2ADUB Peptide, RP4-592A1.1 Peptide, C130067A03Rik Peptide, C530050H10Rik Peptide, RGD1311787 Peptide, 2adub Peptide, Myb like, SWIRM and MPN domains 1 Peptide, myb-like, SWIRM and MPN domains 1 Peptide, Myb like, SWIRM and MPN domains 1 L homeolog Peptide, MYSM1 Peptide, Mysm1 Peptide, mysm1.L Peptide
- 背景
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MYSM1 is a metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. It preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. MYSM1 acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.
Alias Symbols: 2A-DUB, 2ADUB, DKFZp779J1554, DKFZp779J1721, KIAA1915, RP4-592A1.1
Protein Size: 828 - 分子量
- 91 kDa
- 基因ID
- 114803
- NCBI登录号
- NM_001085487, NP_001078956
- UniProt
- Q5VVJ2
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