Iodotyrosine Deiodinase (IYD) (N-Term) Peptide
IYD
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all IYD products
- IYD (Iodotyrosine Deiodinase (IYD))
- 蛋白结构域
- N-Term
- 宿主
- 人
- 资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- NADRSMEKKK GEPRTRAEAR PWVDEDLKDS SDLHQAEEDA DEWQESEENV
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-IYD Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- IYD (Iodotyrosine Deiodinase (IYD))
- 别名
- MGC85450 Peptide, C6orf71 Peptide, DEHAL1 Peptide, TDH4 Peptide, dJ422F24.1 Peptide, 0610009A07Rik Peptide, AI265638 Peptide, Dehal1 Peptide, RGD1309288 Peptide, IYD-1 Peptide, iodotyrosine deiodinase Peptide, iodotyrosine deiodinase L homeolog Peptide, IYD Peptide, iyd.L Peptide, iyd Peptide, Iyd Peptide
- 背景
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This gene encodes an enzyme that catalyzes the oxidative NADPH-dependent deiodination of mono- and diiodotyrosine, which are the halogenated byproducts of thyroid hormone production. The N-terminus of the protein functions as a membrane anchor. Mutations in this gene cause congenital hypothyroidism due to dyshormonogenesis type 4, which is also referred to as deiodinase deficiency, or iodotyrosine dehalogenase deficiency, or thyroid hormonogenesis type 4.
Alias Symbols: C6orf71, DEHAL1, TDH4, dJ422F24.1
Protein Size: 247 - 分子量
- 27 kDa
- 基因ID
- 389434
- NCBI登录号
- NM_001164695, NP_001158167
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