V-Ral Simian Leukemia Viral Oncogene Homolog B (Ras Related, GTP Binding Protein) (Ralb) (Middle Region) Peptide
Ralb
适用: 人, 小鼠
宿主: 合成
BP, WB
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- 抗原 See all RALB (Ralb) products
- RALB (Ralb) (V-Ral Simian Leukemia Viral Oncogene Homolog B (Ras Related, GTP Binding Protein) (Ralb))
- 蛋白结构域
- Middle Region
- 宿主
- 人, 小鼠
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- EHESFTATAE FREQILRVKS EEDKIPLLVV GNKSDLEERR QVPVDEARGK
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-Ralb Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- RALB (Ralb) (V-Ral Simian Leukemia Viral Oncogene Homolog B (Ras Related, GTP Binding Protein) (Ralb))
- 别名
- dRalb Peptide, 5730472O18Rik Peptide, Ral B Peptide, ralb Peptide, xralb Peptide, zgc:100801 Peptide, KRAS2 Peptide, k-ras Peptide, RAS like proto-oncogene B Peptide, v-ral simian leukemia viral oncogene B Peptide, v-ral simian leukemia viral oncogene homolog B L homeolog Peptide, v-ral simian leukemia viral oncogene homolog Ba (ras related) Peptide, v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) Peptide, RALB Peptide, Ralb Peptide, ralb.L Peptide, ralba Peptide, ralb Peptide
- 背景
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Ralb is a multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Ralb accomplishes its multiple functions by interacting with distinct downstream effectors. It acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. It is required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells. Ralb plays a role in the late stages of cytokinesis and is required for the abscission of the bridge joining the sister cells emerging from mitosis. It is required for suppression of apoptosis.
Alias Symbols: 5730472O18Rik
Protein Size: 206 - 分子量
- 23 kDa
- 基因ID
- 64143
- NCBI登录号
- NM_022327, NP_071722
- UniProt
- Q9JIW9
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