Activating Transcription Factor 7 Interacting Protein (ATF7IP) (Middle Region) Peptide
ATF7IP
适用: 人, 小鼠
宿主: 合成
BP, WB
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- 抗原 See all MCAF1 (ATF7IP) products
- MCAF1 (ATF7IP) (Activating Transcription Factor 7 Interacting Protein (ATF7IP))
- 蛋白结构域
- Middle Region
- 宿主
- 人, 小鼠
- 资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- MSTPEGEKSE KDGKAEEEER VPAEEQPPVR NEFSRRKRSK SEDMDSVESK
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-Atf7ip Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- MCAF1 (ATF7IP) (Activating Transcription Factor 7 Interacting Protein (ATF7IP))
- 别名
- ATF7IP Peptide, AM Peptide, MCAF Peptide, MCAF1 Peptide, p621 Peptide, 2610204M12Rik Peptide, Mcaf1 Peptide, fa12g02 Peptide, wu:fa12g02 Peptide, zgc:152981 Peptide, activating transcription factor 7 interacting protein Peptide, Atf7ip Peptide, ATF7IP Peptide, atf7ip Peptide
- 背景
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Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Atf7ip can both act as an activator or a repressor depending on the context. It mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. Atf7ip is required to stimulate histone methyltransferase activity of SETDB1 and facilitate the conversion of dimethylated to trimethylated H3 'Lys-9' (H3K9me3). The complex formed with MBD1 and SETDB1 represses transcription and couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3). Atf7ip may have ATPase activity.
Alias Symbols: 2610204M12Rik, AM, Mcaf1
Protein Size: 1306 - 分子量
- 138 kDa
- 基因ID
- 54343
- NCBI登录号
- NM_019426, NP_062299
- UniProt
- Q7TT18
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