PDE8B 抗体
(phosphodiesterase 8B (PDE8B))
The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010].
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PDE8B
适用: 人, 小鼠, 马, Cow, 猴, 犬, Pig, 大鼠, Bat, 小鸡, 非洲爪蟾
WB
宿主: 兔
Polyclonal
unconjugated
Latest Publications for our PDE8B 抗体
: "Haplotype analysis of the promoter region of phosphodiesterase type 8B (PDE8B) in correlation with inactivating PDE8B mutation and the serum thyroid-stimulating hormone levels." in: Thyroid : official journal of the American Thyroid Association, Vol. 20, Issue 4, pp. 363-7, (2010) (PubMed).: "Phosphodiesterase 8B gene polymorphism is associated with subclinical hypothyroidism in pregnancy." in: The Journal of clinical endocrinology and metabolism, Vol. 94, Issue 11, pp. 4608-12, (2009) (PubMed).
: "Abnormalities of cAMP signaling are present in adrenocortical lesions associated with ACTH-independent Cushing syndrome despite the absence of mutations in known genes." in: European journal of endocrinology / European Federation of Endocrine Societies, Vol. 161, Issue 1, pp. 153-61, (2009) (PubMed).
Aliases for PDE8B 抗体
phosphodiesterase 8B (PDE8B) 抗体high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (LOC100468338) 抗体
phosphodiesterase 8B (pde8b) 抗体
phosphodiesterase 8B (Pde8b) 抗体
ADSD 抗体
B230331L10Rik 抗体
C030047E14Rik 抗体
PDE8B 抗体
PPNAD3 抗体
RNPDE8B 抗体
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