PDE8B 抗体 (Middle Region)
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北京 101111
Quick Overview for PDE8B 抗体 (Middle Region) (ABIN2789902)
抗原
See all PDE8B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- PDE8B Antibody - middle region
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序列
- TELYSPQLGT KDEDPHTSDL VGGLMTDGLR RLSGNEYVFT KNVHQSHSHL
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against PDE8B. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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anti-phosphodiesterase 8B (PDE8B) (Internal Region) antibody
PDE8B 适用: 人, 马, 猴, Bat IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 8B (PDE8B) (AA 296-324) antibodyPDE8B 适用: 小鼠 WB 宿主: 兔 Polyclonal RB42219 unconjugated
anti-phosphodiesterase 8B (PDE8B) (AA 18-110) antibodyPDE8B 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64625-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PDE8B (phosphodiesterase 8B (PDE8B))
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别名
- PDE8B
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背景
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Background Information: The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.
Gene Name: Phosphodiesterase 8B
Alternative Symbols: ADSD, PPNAD3
Protein Name: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
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分子量
- 87kDa
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基因ID
- 8622
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NCBI登录号
- NP_001025022
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UniProt
- O95263
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途径
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process
抗原
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