PDE10A 抗体
(phosphodiesterase 10A (PDE10A))
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2011].
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25 results
PDE10A
适用: 人, 大鼠, 小鼠, 猴
WB, ELISA, IHC, IP, ICC, IF, CM
宿主: 兔
Polyclonal
FITC
Latest Publications for our PDE10A 抗体
: "Cyclic nucleotide phosphodiesterases in human spermatozoa and seminal fluid: Presence of an active PDE10A in human spermatozoa." in: Biochimica et biophysica acta, Vol. 1861, Issue 2, pp. 147-156, (2017) (PubMed).: "Identification and Localization of the Cyclic Nucleotide Phosphodiesterase 10A in Bovine Testis and Mature Spermatozoa." in: PLoS ONE, Vol. 11, Issue 8, pp. e0161035, (2016) (PubMed).
: "Phosphodiesterase 10A: a novel target for selective inhibition of colon tumor cell growth and β-catenin-dependent TCF transcriptional activity." in: Oncogene, Vol. 34, Issue 12, pp. 1499-509, (2015) (PubMed).
: "Characterization of the binding properties of T-773 as a PET radioligand for phosphodiesterase 10A." in: Nuclear medicine and biology, Vol. 42, Issue 2, pp. 146-54, (2015) (PubMed).
: "Levodopa-induced dyskinesias are associated with transient down-regulation of cAMP and cGMP in the caudate-putamen of hemiparkinsonian rats: reduced synthesis or increased catabolism?" in: Neurochemistry international, Vol. 79, pp. 44-56, (2015) (PubMed).
: "Phosphodiesterase 10A controls D1-mediated facilitation of GABA release from striato-nigral projections under normal and dopamine-depleted conditions." in: Neuropharmacology, Vol. 76 Pt A, pp. 127-36, (2014) (PubMed).
: "Phosphodiesterase 2 inhibitors promote axonal outgrowth in organotypic slice co-cultures." in: Neuro-Signals, Vol. 21, Issue 3-4, pp. 197-212, (2013) (PubMed).
: "Phosphodiesterase 10A upregulation contributes to pulmonary vascular remodeling." in: PLoS ONE, Vol. 6, Issue 4, pp. e18136, (2011) (PubMed).
: "PDE10A and PDE10A-dependent cAMP catabolism are dysregulated oppositely in striatum and nucleus accumbens after lesion of midbrain dopamine neurons in rat: a key step in parkinsonism physiopathology." in: Neurobiology of disease, Vol. 43, Issue 1, pp. 293-303, (2011) (PubMed).
: "The role of the PDE4D cAMP phosphodiesterase in the regulation of glucagon-like peptide-1 release." in: British journal of pharmacology, Vol. 157, Issue 4, pp. 633-44, (2009) (PubMed).
Aliases for PDE10A 抗体
phosphodiesterase 10A (PDE10A) 抗体phosphodiesterase 10A (Pde10a) 抗体
HSPDE10A 抗体
Pde10a3 抗体
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