PDL2 Detection Set (Risk Free)
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- 抗原 See all PDCD1LG2 products
- PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
- 抗原表位
- Extracellular Domain
- 适用
- 人
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宿主
- 小鼠
- 克隆类型
- 单克隆
- 应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 品牌
- Risk-Free™
- 产品特性
- Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PD-L1 and PD-L2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PD-L2 can act to stimulate an immunogenic response through an alternative receptor from PD-1.
- 纯化方法
- Antibodies are supplied as protein A purified IgG1.
- 组件
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PD-L2 Antibody [4E10]
PD-L2 Antibody [8C12]
PD-L2 Antibody [7C7]
PD-L2 Antibody [7C1]
PD-L2 Antibody [10H4] - 免疫原
- Mouse monoclonal PD-L2 antibodies were raised against the extracellular domain of human PD-L2.
- 亚型
- IgG1
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- 说明
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Risk-Free™ antibodies are monoclonal antibodies made to improve in vitro studies.
Unlike antibodies developed using proteins made in yeast or bacteria, Risk-Free™ antibodies are developed with antigens expressed in mammalian cell lines, giving the most native post-translational modifications to the protein.
These antibodies have the following advantages:
- Antibodies are developed against mammalian-expressed, post-translationally modified recombinant proteins.
- Multiple antibodies per target allows the user to choose the best antibody for their application
- Available individually or as a set
- Risk-Free™ means they are rigorously tested and guaranteed to work for their designated applications:
- ELISA
- Flow Cytometry
- Immunoblot
- Immunohistochemistry
- Immunocytochemistry
- Immunofluorescence - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- 抗原
- PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
- 别名
- PDL2 (PDCD1LG2 产品)
- 别名
- PDL2 Matched Antibody Pair, B7DC Matched Antibody Pair, Btdc Matched Antibody Pair, CD273 Matched Antibody Pair, PD-L2 Matched Antibody Pair, PDCD1L2 Matched Antibody Pair, bA574F11.2 Matched Antibody Pair, B7-DC Matched Antibody Pair, F730015O22Rik Matched Antibody Pair, programmed cell death 1 ligand 2 Matched Antibody Pair, PDCD1LG2 Matched Antibody Pair, Pdcd1lg2 Matched Antibody Pair
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