NUB1 抗体
(Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1))
This gene encodes a protein that functions as a negative regulator of NEDD8, a ubiquitin-like protein that conjugates with cullin family members in order to regulate vital biological events. The protein encoded by this gene regulates the NEDD8 conjugation system post-transcriptionally by recruiting NEDD8 and its conjugates to the proteasome for degradation. This protein interacts with the product of the AIPL1 gene, which is associated with Leber congenital amaurosis, an inherited retinopathy, and mutations in that gene can abolish interaction with this protein, which may contribute to the pathogenesis. This protein is also known to accumulate in Lewy bodies in Parkinson's disease and dementia with Lewy bodies, and in glial cytoplasmic inclusions in multiple system atrophy, with this abnormal accumulation being specific to alpha-synucleinopathy lesions. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011].
Recommended next Filters:
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
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| NUB1 抗体 (Alexa Fluor 680) | 人 | 兔 Polyclonal |
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| NUB1 抗体 (Alexa Fluor 555) | 人 | 兔 Polyclonal |
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| NUB1 抗体 (Alexa Fluor 647) | 人 | 兔 Polyclonal |
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| NUB1 抗体 (Alexa Fluor 750) | 人 | 兔 Polyclonal |
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| NUB1 抗体 (Alexa Fluor 488) | 人 | 兔 Polyclonal |
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| NUB1 抗体 (Alexa Fluor 594) | 人 | 兔 Polyclonal |
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| NUB1 抗体 (AA 190-543) | 人, 小鼠, 猴, 大鼠 | 兔 Polyclonal |
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| NUB1 抗体 (Biotin) | 人 | 兔 Polyclonal |
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| NUB1 抗体 (AA 87-117) | 人, 小鼠 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人, 小鼠, 猴, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 190-543
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 87-117
筛选 1 个已启用筛选
Latest Publications for our NUB1 抗体
: "Regulation of the NEDD8 conjugation system by a splicing variant, NUB1L." in: The Journal of biological chemistry, Vol. 278, Issue 35, pp. 32905-13, (2003) (PubMed).
: "The inherited blindness associated protein AIPL1 interacts with the cell cycle regulator protein NUB1." in: Human molecular genetics, Vol. 11, Issue 22, pp. 2723-33, (2002) (PubMed).
: "NUB1, a NEDD8-interacting protein, is induced by interferon and down-regulates the NEDD8 expression." in: The Journal of biological chemistry, Vol. 276, Issue 23, pp. 20603-9, (2001) (PubMed).
: "The inherited blindness associated protein AIPL1 interacts with the cell cycle regulator protein NUB1." in: Human molecular genetics, Vol. 11, Issue 22, pp. 2723-33, (2002) (PubMed).
: "NUB1, a NEDD8-interacting protein, is induced by interferon and down-regulates the NEDD8 expression." in: The Journal of biological chemistry, Vol. 276, Issue 23, pp. 20603-9, (2001) (PubMed).
Aliases for NUB1 抗体
negative regulator of ubiquitin-like proteins 1 (Nub1) 抗体negative regulator of ubiquitin like proteins 1 (NUB1) 抗体
4931404D21Rik 抗体
6330412F12Rik 抗体
BS4 抗体
NUB1L 抗体
NY-REN-18 抗体
NYREN18 抗体
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