NUB1 抗体 (AA 190-543)
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Quick Overview for NUB1 抗体 (AA 190-543) (ABIN7871644)
抗原
See all NUB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 190-543
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原理
- NUB1 Antibody / NEDD8 ultimate buster 1 / NYREN18
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived human recombinant protein (K190-D543) was used as the immunogen for the NUB1 antibody.
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亚型
- IgG
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anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) (AA 1-326) antibody
NUB1 适用: 人, 猴, 大鼠, 犬 WB, IHC, IHC (p), IF, FACS 宿主: 小鼠 Monoclonal 4H2 unconjugated
anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) (AA 1-326) antibodyNUB1 适用: 人 WB, IHC, IHC (p), FACS 宿主: 小鼠 Monoclonal 2G1 unconjugated
anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) antibodyNUB1 适用: 人, 小鼠, 猴 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) (AA 87-117), (N-Term) antibodyNUB1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB2874 unconjugated
anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) (C-Term) antibodyNUB1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) (AA 513-542), (C-Term) antibodyNUB1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB2875 unconjugated
anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) (AA 1-601) antibodyNUB1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) antibodyNUB1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB15825 unconjugated
anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) (C-Term) antibodyNUB1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) (C-Term) antibodyNUB1 适用: 人, 小鼠, 猴 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the NUB1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the NUB1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- NUB1 (Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1))
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别名
- NUB1
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背景
- NEDD8 µLtimate buster 1 is a protein that in humans is encoded by the NUB1 gene. This gene encodes a protein that functions as a negative regulator of NEDD8, a ubiquitin-like protein that conjugates with cullin family members in order to regulate vital biological events. The protein encoded by this gene regulates the NEDD8 conjugation system post-transcriptionally by recruiting NEDD8 and its conjugates to the proteasome for degradation. This protein interacts with the product of the AIPL1 gene, which is associated with Leber congenital amaurosis, an inherited retinopathy, and mutations in that gene can abolish interaction with this protein, which may contribute to the pathogenesis. This protein is also known to accumulate in Lewy bodies in Parkinson's disease and dementia with Lewy bodies, and in glial cytoplasmic inclusions in multiple system atrophy, with this abnormal accumulation being specific to alpha-synucleinopathy lesions. Alternative splicing of this gene results in multiple transcript variants.
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UniProt
- Q9Y5A7
抗原
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