NTAN1 抗体
(N-terminal Asparagine Amidase (NTAN1))
The protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp. L-Asp substrates are subsequently conjugated to L-Arg, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of chromosomes 8, 10 and 12. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012].
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Latest Publications for our NTAN1 抗体
: "Ectopic high endothelial venules in pancreatic ductal adenocarcinoma: A unique site for targeted delivery." in: EBioMedicine, Vol. 38, pp. 79-88, (2019) (PubMed).: "Anti-IL-6 eluting immunomodulatory biomaterials prolong skin allograft survival." in: Scientific reports, Vol. 9, Issue 1, pp. 6535, (2019) (PubMed).
: "Tertiary lymphoid organs in the inflammatory myopathy associated with PD-1 inhibitors." in: Journal for immunotherapy of cancer, Vol. 7, Issue 1, pp. 256, (2019) (PubMed).
: "Targeted delivery of immune therapeutics to lymph nodes prolongs cardiac allograft survival." in: The Journal of clinical investigation, Vol. 128, Issue 11, pp. 4770-4786, (2018) (PubMed).
: "microRNA-125a-3p is regulated by MyD88 in Legionella pneumophila infection and targets NTAN1." in: PLoS ONE, Vol. 12, Issue 4, pp. e0176204, (2017) (PubMed).
: "Lymphoid neogenesis in skin of human hand, nonhuman primate, and rat vascularized composite allografts." in: Transplant international : official journal of the European Society for Organ Transplantation, Vol. 27, Issue 9, pp. 966-76, (2014) (PubMed).
: "Novel anti-carbohydrate antibodies reveal the cooperative function of sulfated N- and O-glycans in lymphocyte homing." in: The Journal of biological chemistry, Vol. 285, Issue 52, pp. 40864-78, (2010) (PubMed).
: "Aberrant endometrial features of pregnancy in diabetic NOD mice." in: Diabetes, Vol. 56, Issue 12, pp. 2919-26, (2007) (PubMed).
: "Ectopic LT alpha beta directs lymphoid organ neogenesis with concomitant expression of peripheral node addressin and a HEV-restricted sulfotransferase." in: The Journal of experimental medicine, Vol. 197, Issue 9, pp. 1153-63, (2003) (PubMed).
: "Human endomucin: distribution pattern, expression on high endothelial venules, and decoration with the MECA-79 epitope." in: The American journal of pathology, Vol. 160, Issue 5, pp. 1669-81, (2002) (PubMed).
Aliases for NTAN1 抗体
N-terminal Asn amidase (Ntan1) 抗体N-terminal asparagine amidase (NTAN1) 抗体
PNAA 抗体
PNAD 抗体
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