NOXA 抗体
(Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))
Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
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| NOXA 抗体 (Alexa Fluor 555) | 人 | 兔 Polyclonal |
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| Recombinant NOXA 抗体 (Biotin) | 人 | 兔 Monoclonal |
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| Recombinant NOXA 抗体 (Alexa Fluor 680) | 人 | 兔 Monoclonal |
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| NOXA 抗体 (Alexa Fluor 680) | 人 | 兔 Polyclonal |
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| Recombinant NOXA 抗体 (Alexa Fluor 647) | 人 | 兔 Monoclonal |
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| NOXA 抗体 (Alexa Fluor 647) | 人 | 兔 Polyclonal |
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| Recombinant NOXA 抗体 (Alexa Fluor 750) | 人 | 兔 Monoclonal |
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| NOXA 抗体 (Alexa Fluor 750) | 人 | 兔 Polyclonal |
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| Recombinant NOXA 抗体 (Alexa Fluor 488) | 人 | 兔 Monoclonal |
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| NOXA 抗体 (Alexa Fluor 488) | 人 | 兔 Polyclonal |
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| Recombinant NOXA 抗体 (Alexa Fluor 594) | 人 | 兔 Monoclonal |
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| NOXA 抗体 (Alexa Fluor 594) | 人 | 兔 Polyclonal |
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| NOXA 抗体 (AA 51-66) | 小鼠 | 兔 Polyclonal |
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| NOXA 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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Primary Antibody
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Biotin
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 680
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 647
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 750
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 488
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Alexa Fluor 594
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 51-66
Latest Publications for our NOXA 抗体
: "MARCH5-dependent degradation of MCL1/NOXA complexes defines susceptibility to antimitotic drug treatment." in: Cell death and differentiation, Vol. 27, Issue 8, pp. 2297-2312, (2021) (PubMed).
: "Genome-scale CRISPR screening for potential targets of ginsenoside compound K." in: Cell death & disease, Vol. 11, Issue 1, pp. 39, (2021) (PubMed).
: "HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma." in: International journal of cancer, Vol. 142, Issue 9, pp. 1926-1937, (2019) (PubMed).
: "Targeting prosurvival BCL2 signaling through Akt blockade sensitizes castration-resistant prostate cancer cells to enzalutamide." in: The Prostate, Vol. 79, Issue 11, pp. 1347-1359, (2019) (PubMed).
: "Targeting STAT5 or STAT5-Regulated Pathways Suppresses Leukemogenesis of Ph+ Acute Lymphoblastic Leukemia." in: Cancer research, Vol. 78, Issue 20, pp. 5793-5807, (2018) (PubMed).
: "Mannose impairs tumour growth and enhances chemotherapy." in: Nature, Vol. 563, Issue 7733, pp. 719-723, (2018) (PubMed).
: "Essential role for Bim in mediating the apoptotic and antitumor activities of immunotoxins." in: Oncogene, Vol. 36, Issue 35, pp. 4953-4962, (2017) (PubMed).
: "Deletion of the BH3-only protein Noxa alters electrographic seizures but does not protect against hippocampal damage after status epilepticus in mice." in: Cell death & disease, Vol. 8, Issue 1, pp. e2556, (2017) (PubMed).
: "Bax/Bak activation in the absence of Bid, Bim, Puma, and p53." in: Cell death & disease, Vol. 7, pp. e2266, (2016) (PubMed).
: "p73 engages A2B receptor signalling to prime cancer cells to chemotherapy-induced death." in: Oncogene, (2015) (PubMed).
: "Genome-scale CRISPR screening for potential targets of ginsenoside compound K." in: Cell death & disease, Vol. 11, Issue 1, pp. 39, (2021) (PubMed).
: "HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma." in: International journal of cancer, Vol. 142, Issue 9, pp. 1926-1937, (2019) (PubMed).
: "Targeting prosurvival BCL2 signaling through Akt blockade sensitizes castration-resistant prostate cancer cells to enzalutamide." in: The Prostate, Vol. 79, Issue 11, pp. 1347-1359, (2019) (PubMed).
: "Targeting STAT5 or STAT5-Regulated Pathways Suppresses Leukemogenesis of Ph+ Acute Lymphoblastic Leukemia." in: Cancer research, Vol. 78, Issue 20, pp. 5793-5807, (2018) (PubMed).
: "Mannose impairs tumour growth and enhances chemotherapy." in: Nature, Vol. 563, Issue 7733, pp. 719-723, (2018) (PubMed).
: "Essential role for Bim in mediating the apoptotic and antitumor activities of immunotoxins." in: Oncogene, Vol. 36, Issue 35, pp. 4953-4962, (2017) (PubMed).
: "Deletion of the BH3-only protein Noxa alters electrographic seizures but does not protect against hippocampal damage after status epilepticus in mice." in: Cell death & disease, Vol. 8, Issue 1, pp. e2556, (2017) (PubMed).
: "Bax/Bak activation in the absence of Bid, Bim, Puma, and p53." in: Cell death & disease, Vol. 7, pp. e2266, (2016) (PubMed).
: "p73 engages A2B receptor signalling to prime cancer cells to chemotherapy-induced death." in: Oncogene, (2015) (PubMed).
Aliases for NOXA 抗体
phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1) 抗体phorbol-12-myristate-13-acetate-induced protein 1 (pmaip1) 抗体
phorbol-12-myristate-13-acetate-induced protein 1 (Pmaip1) 抗体
APR 抗体
NOXA 抗体
Noxa 抗体
PMAIP1 抗体
TN3 抗体
zgc:162379 抗体
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