NOXA 抗体
(Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))
Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.
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33 results :
PMAIP1
适用: 人
ELISA, FACS
宿主: 小鼠
Monoclonal
1A2D3
unconjugated
Rockland Original
PMAIP1
适用: 人, 小鼠, 大鼠
WB, IHC (p), EIA
宿主: 兔
Polyclonal
unconjugated
PMAIP1
适用: 人
ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
PMAIP1
适用: 人
WB
宿主: 兔
Monoclonal
R01-5G3R01-5G3
unconjugated
Recombinant Antibody
Latest Publications for our NOXA 抗体
: "MARCH5-dependent degradation of MCL1/NOXA complexes defines susceptibility to antimitotic drug treatment." in: Cell death and differentiation, Vol. 27, Issue 8, pp. 2297-2312, (2021) (PubMed).: "Genome-scale CRISPR screening for potential targets of ginsenoside compound K." in: Cell death & disease, Vol. 11, Issue 1, pp. 39, (2021) (PubMed).
: "HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma." in: International journal of cancer, Vol. 142, Issue 9, pp. 1926-1937, (2019) (PubMed).
: "Targeting prosurvival BCL2 signaling through Akt blockade sensitizes castration-resistant prostate cancer cells to enzalutamide." in: The Prostate, Vol. 79, Issue 11, pp. 1347-1359, (2019) (PubMed).
: "Targeting STAT5 or STAT5-Regulated Pathways Suppresses Leukemogenesis of Ph+ Acute Lymphoblastic Leukemia." in: Cancer research, Vol. 78, Issue 20, pp. 5793-5807, (2018) (PubMed).
: "Mannose impairs tumour growth and enhances chemotherapy." in: Nature, Vol. 563, Issue 7733, pp. 719-723, (2018) (PubMed).
: "Essential role for Bim in mediating the apoptotic and antitumor activities of immunotoxins." in: Oncogene, Vol. 36, Issue 35, pp. 4953-4962, (2017) (PubMed).
: "Deletion of the BH3-only protein Noxa alters electrographic seizures but does not protect against hippocampal damage after status epilepticus in mice." in: Cell death & disease, Vol. 8, Issue 1, pp. e2556, (2017) (PubMed).
: "Bax/Bak activation in the absence of Bid, Bim, Puma, and p53." in: Cell death & disease, Vol. 7, pp. e2266, (2016) (PubMed).
: "p73 engages A2B receptor signalling to prime cancer cells to chemotherapy-induced death." in: Oncogene, (2015) (PubMed).
Aliases for NOXA 抗体
phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1) 抗体phorbol-12-myristate-13-acetate-induced protein 1 (pmaip1) 抗体
phorbol-12-myristate-13-acetate-induced protein 1 (Pmaip1) 抗体
APR 抗体
NOXA 抗体
Noxa 抗体
PMAIP1 抗体
TN3 抗体
zgc:162379 抗体
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