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抗Human Tumor Necrosis Factor 抗体:
抗Rat (Rattus) Tumor Necrosis Factor 抗体:
抗Mouse (Murine) Tumor Necrosis Factor 抗体:
Mouse (Murine) Polyclonal Tumor Necrosis Factor Primary Antibody for CyTOF, ELISA (Capture) - ABIN4900489
Ramkhelawon, Hennessy, Ménager, Ray, Sheedy, Hutchison, Wanschel, Oldebeken, Geoffrion, Spiro, Miller, McPherson, Rayner, Moore: Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity. in Nature medicine 2014
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Rat (Rattus) Polyclonal Tumor Necrosis Factor Primary Antibody for WB - ABIN3042522
Zhang, Liu, Goldstein, Li, Ge, He, Fei, Wang, Ruiz: Role of the JAK/STAT signaling pathway in the pathogenesis of acute myocardial infarction in rats and its effect on NF-?B expression. in Molecular medicine reports 2013
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Mouse (Murine) Polyclonal Tumor Necrosis Factor Primary Antibody for WB - ABIN3043313
Liu, Shan, Dong, Liu, Ma, Liu: Combined early fluid resuscitation and hydrogen inhalation attenuates lung and intestine injury. in World journal of gastroenterology 2013
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Mouse (Murine) Polyclonal Tumor Necrosis Factor Primary Antibody for ELISA, IHC (p) - ABIN3042817
Qin, Ma, Yang, Hu, Zhou, Fu, Tian, Liu, Xu, Shen: A Triterpenoid Inhibited Hormone-Induced Adipocyte Differentiation and Alleviated Dexamethasone-Induced Insulin Resistance in 3T3-L1 adipocytes. in Natural products and bioprospecting 2015
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Human Monoclonal Tumor Necrosis Factor Primary Antibody for - ABIN1383955
Hervé, Racadot, Wijdenes, Flesch, Tiberghien, Bordigoni, Holler, Powles, Bourdeau, Wilmer: Monoclonal anti TNF alpha antibody in the treatment of acute GvHD refractory both to corticosteroids and anti IL-2 R antibody. in Bone marrow transplantation 1991
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Human Polyclonal Tumor Necrosis Factor Primary Antibody for ICC, IF - ABIN446837
Kwon, Jung, Hwang, Choi: Evaluation of Bronchiolar and Alveolar Cell Injuries Induced by Short- and Long-term Exposure to Sidestream Smoke. in Korean journal of pathology 2012
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Human Polyclonal Tumor Necrosis Factor Primary Antibody for IF (p), IHC (p) - ABIN677318
Morishita, Oku, Horie, Tonari, Kida, Okubo, Sugiyama, Takai, Hara, Ikeda: Systemic simvastatin rescues retinal ganglion cells from optic nerve injury possibly through suppression of astroglial NF-?B activation. in PLoS ONE 2014
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Human Polyclonal Tumor Necrosis Factor Primary Antibody for IHC (p), IHC - ABIN153474
Roth, Städler, Lemann, Hösli, Simon, Simon: Distinct eosinophil cytokine expression patterns in skin diseases - the possible existence of functionally different eosinophil subpopulations. in Allergy 2011
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Chicken Polyclonal Tumor Necrosis Factor Primary Antibody for IHC, ELISA - ABIN1582141
Choi, Lim, Hwang, Lee, Cho, Kim: Anti-ischemic and anti-inflammatory activity of (S)-cis-verbenol. in Free radical research 2010
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Human Monoclonal Tumor Necrosis Factor Primary Antibody for FACS - ABIN4898910
Glässner, Eisenhardt, Krämer, Körner, Coenen, Sauerbruch, Spengler, Nattermann: NK cells from HCV-infected patients effectively induce apoptosis of activated primary human hepatic stellate cells in a TRAIL-, FasL- and NKG2D-dependent manner. in Laboratory investigation; a journal of technical methods and pathology 2012
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Inter-group comparisons of cytokine levels demonstrated no significant differences in TNF-alpha, IL-6 (显示 IL6 抗体) and IL-8 (显示 IL8 抗体) cytokines levels. IL-10 (显示 IL10 抗体) level showed a moderately significant increase in the modified St. Thomas' group compared to the del Nido group after surgery (2.94+/-0.9 vs. 2.46+/-0.61 log10 pg/mL, respectively; p=0.039).
TNFalpha induced upregulation of MUC4 (显示 MUC4 抗体) that reduced trastuzumab binding to its epitope and impaired ADCC. Administration of TNFalpha-blocking antibodies downregulated MUC4 (显示 MUC4 抗体) and sensitized de novo trastuzumab-resistant breast cancer cells and tumors to trastuzumab.
our findings demonstrated that circulating TNF-alpha was significantly higher in OSAS patients than in controls, and this difference became more pronounced with the more severe grades of OSAS, indicating that TNF-alpha might be a promising circulating biomarker for the development of OSAS.
our findings show that imperatorin inhibits TNF-alpha-induced ROS (显示 ROS1 抗体) generation. Taken together, imperatorin can blunt inflammation by inhibiting the ROS (显示 ROS1 抗体)-mediated activation of the PI3K (显示 PIK3CA 抗体)/Akt (显示 AKT1 抗体)/NF-kappaB (显示 NFKB1 抗体) pathway
TNF-alpha inhibitors decrease histone (H)3 and H4 acetylation in the RORgammat gene promotor region by decreasing the recruitment of the acetyltransferases p300 (显示 EP300 抗体), CBP (显示 CREBBP 抗体) and PCAF (显示 KAT2B 抗体) in Th17 cells, from rheumatoid arthritis patients.
Homozygous genotype TNF-a (-308A/G) was associated with the relative risk of Chronic Respiratory Diseases in foundry workers.
These results indicate that not H1 but M3 receptor-induced activation of p38 MAPK (显示 MAPK14 抗体) might contribute to the maintenance of epithelial barrier function through down-regulation of TNF-alpha signalling and activation of EGFR (显示 EGFR 抗体).
Determined a novel role of TNF-alpha in inducing Bmal1 (显示 ARNTL 抗体) via dual calcium dependent pathways; Roralpha was up-regulated in the presence of Ca(2 (显示 CA2 抗体)+) influx and Rev-erbalpha (显示 NR1D1 抗体) was down-regulated in the absence of that.
Inhibiting tumor necrosis factor-alpha diminishes desmoplasia and inflammation to overcome chemoresistance in pancreatic ductal adenocarcinoma cells.
Calyptranthes grandifolia O.Berg (Myrtaceae) ethanolic extract inhibits TNF-alpha gene expression and cytokine release in vitro
Inhibition of signaling stimulated by both TNF and IL1beta (显示 IL1B 抗体) synergizes with NF-kappaB (显示 NFKB1 抗体) inhibition in eliminating leukemic stem cells.
Results show that interleukin 6 (IL6 (显示 IL6 抗体)) promotes oval cell proliferation and liver regeneration, while tumor necrosis factor alpha (TNFalpha) and TNF receptor-1(TNFR1 (显示 TNFRSF1A 抗体)) do not affect this process.
This study adds to the evidence that both peripheral and brain region-specific increases in tumor necrosis factor alpha lead to both sickness and depression- and anxiety disorder-relevant behavior and do so via different pathways.
Lactosylceramide-Induced Phosphorylation Signaling to Group IVA Phospholipase A2 (显示 YWHAZ 抗体) via Reactive Oxygen Species in Tumor Necrosis Factor-alpha-Treated Cells.
The current study demonstrated that honey can stimulate or suppress the mRNA expression of some pro-inflammatory cytokines in mice brains. Furthermore, honey suppresses the TNF-alpha mRNA expression in the presence of T. gondii infection but it stimulates the IL-1beta (显示 IL1B 抗体) and IL-6 (显示 IL6 抗体) mRNA expression. Treatment of the mice with honey reduces parasite multiplication in the brain.
aerobic interval training enhanced the anti-inflammatory indices IL-10 (显示 IL10 抗体)/TNF-alpha ratio and IL-15 (显示 IL15 抗体) expression in skeletal muscle in tumor-bearing mice.
findings suggest that activation of Tnf-Aicda (显示 AICDA 抗体) axis and co-inhibitory signals to T cells in coordination with Th1 (显示 HAND1 抗体)-type immunity has critical roles in the immune response against Hepatitis B virus infection
Taken together, we speculate that DT-13 inhibits endothelium vascular inflammation through regulating nitric oxide production and the expression of ROS (显示 ROS1 抗体), TNFR (显示 TNFRSF1A 抗体), IL-8 (显示 IL8 抗体), MCP-1 (显示 CPT1B 抗体), which are associated with inflammation.
TNF signalling is required for the expansion and differentiation of pathogenic IFNgamma+CD4 (显示 CD4 抗体)+ T cells that promote the irreversible loss of bone marrow function.
Data suggest that luteolytic factors (such as TNFa, interferon gamma (显示 IFNG 抗体), and PGF2a) control expression of MMP1 (显示 MMP1 抗体), other matrix metalloproteinases, and tissue inhibitors of metalloproteinase in cultured luteal cells.
These results suggest that polymorphism of the TNFalpha-824 A>G gene and mTNFalpha protein expression play an important role in the pathogenesis of enzootic bovine leukosis.
These results suggest that the endometrium might lower the TNF concentration in the blastocyst by (1) regulating TNF secretion into the uterine fluid and (2) inducing decreased TNF and TNFR2 (显示 TNFRSF1B 抗体) mRNA transcription in the embryo.
There was a significant association between the proviral load and a low frequency of the G/G genotype of TNF-alpha at position -824.
SNP in the TNF-alpha gene affects immune function and reproductive performance in dairy cows.
Studied genotypic and expression profiling of partial TNF-alpha gene and its association with mastitis susceptibility in 129 crossbred cattle.
Messenger RNA and protein levels of prostaglandin (PG) E synthase (PGES (显示 PTGES 抗体)), PGF2alpha receptor (PGFR), tumor necrosis factor-alpha (TNF) and Fas (显示 FAS 抗体) were found to be higher in the corpus luteum of pregnancy than in corpus luteum of the cycle.
TNF-alpha up-regulates NaV1.7 (显示 SCN9A 抗体) mRNA in both adrenal chromaffin cells and dorsal root ganglia (DRG) neurons, highlighting the peripheral nociceptive mechanism of TNF-alpha
These results provide evidence for a high prevalence of subclinical endometritis in repeat breeding cows as well as the involvement of TNFalpha and iNOS (显示 NOS2 抗体) pathways in the regulation of this pathological condition.
Exposure to follicular fluid transiently increased the transcript levels of IL8 (显示 IL8 抗体) and PTGS2 (显示 PTGS2 抗体), and decreased the expression of SOD2 (显示 SOD2 抗体), GPX3 (显示 GPX3 抗体), DAB2 (显示 DAB2 抗体), and NR3C1 (显示 NR3C1 抗体). TNF and IL6 (显示 IL6 抗体) levels were also decreased while those of NAMPT (显示 NAMPT 抗体) were unaffected.
these findings provide the direct evidence that ADAM17 (显示 ADAM17 抗体) cleaves porcine TNFalpha, which represents a new view for identifying potential therapeutic targets in anti-porcine reproductive and respiratory syndrome virus therapy
TMZ pretreatment effectively reduced the myocardial damage caused by CME via inhibiting the PDCD4 (显示 PDCD4 抗体)/NF-kappaB (显示 NFKB1 抗体)/ TNF-alpha pathway in cardiomyocytes.
TNF-alpha, secreted from activated Monocytes, mediates the downregulation of OTX2 (显示 OTX2 抗体) and essential retinal pigment epithelium genes.
TNF-alpha induced MMP-13 (显示 MMP13 抗体) expression by condylar cells might be involved in the degradation of the juvenile condyle.
TNF-alpha was able to promote theca interna cell proliferation. Our results suggest that TNF-alpha might play a role in hyperandrogenism, cortex thickness, and the increased ovary volume observed in polycystic ovaries.
This study showed that the -791(C-->T) mutation of the TNF-alpha gene could be considered an important potential genetic marker of enterotoxigenic Escherichia coli F18 (显示 MAMLD1 抗体) resistance.
Both Nsp1beta and Nsp11 of porcine reproductive and respiratory syndrome virus were demonstrated to be responsible for the inhibitory effect on TNF-alpha production in pulmonary alveolar macrophages.
Study presents evidence demonstrating a single species of exotoxin ApxI, derived from A. pleuropneumoniae serotype 10, induces the expression and production of proinflammatory cytokines IL-1beta (显示 IL1B 抗体), IL-8 (显示 IL8 抗体) and TNF-alpha in porcine alveolar macrophages.
the role of miR (显示 MYLIP 抗体)-181a in adipocyte differentiation by regulation of TNF-alpha
The NOS (显示 NOS 抗体) inhibitor, L-NMMA, significantly suppressed the combined effects of HT and CORM-2 on TNFalpha-triggered NFkappaBp65 phosphorylation as well as decreased cell viability.
Using in vivo, time-lapse imaging we show that as centrally-projecting pioneer axons from dorsal root ganglia (DRG (显示 COL4A1 抗体)) enter the spinal cord, they initiate expression of the cytokine TNFalpha. This induction coincides with ensheathment of these axons by associated glia via a TNF receptor 2 (TNFR2 (显示 TNFRSF1B 抗体))-mediated process.
The results reveal a crucial role for TNFalpha/TNFR2 (显示 TNFRSF1B 抗体) axis in the protection of the skin against DUOX1 (显示 DUOX1 抗体)-mediated oxidative stress.
proinflammatory cytokines IL-1 (显示 IL1A 抗体)/TNFalpha trigger a novel antiviral mechanism involving AID to regulate host cell permissiveness to HBV infection.
TNF alpha is the first molecule identified that is produced by dying retinal neurons and is necessary to induce Muller glia to proliferate in the zebrafish retinal regeneration response.
The data suggest that Mycobacterium marinum SecA2 modulates adaptive immunity to promote granuloma stability, perhaps through induction of tumor necrosis factor alpha.
The data suggest that during infectious pancreatic necrosis virus infection, the expression of cytokines and metalloproteinases might be initiated through the TNFalpha/NF-kappaB (显示 NFKB1 抗体)-mediated pathway.
Infectious pancreatic necrosis virus triggers two death pathways via up-stream induction of the pro-inflammatory cytokine TNFalpha.
Antisense knockdown of tnfa rescued hepatic steatosis and liver degeneration in dtp (显示 AHCY 抗体) larvae, whereas the overexpression of tnfa and the hepatic phenotype were unchanged in dtp (显示 AHCY 抗体) larvae.
TNF is not required for tuberculous granuloma formation, but maintains granuloma integrity indirectly by restricting mycobacterial growth within macrophages and preventing their necrosis.
The main proinflammatory effects of fish TNF-alpha are mediated through the activation of endothelial cells and point to the complexity of the evolution that has taken place in the regulation of innate immunity by cytokines.
These interactions result in the induction of the TNF signaling pathway, activation of apoptosis, and DNA-damage stress response.
Findings showed that both mucosal compartments harbor similar percentages of memory CD4 (显示 CD4 抗体)(+) T cells and displayed comparable cytokine TNF-alpha responses to mitogenic stimulations prior to infection.
Primary role for IL-1beta (显示 IL1B 抗体) and TNF-alpha in the triggering of preterm labor associated with inflammation or infection.
The results obtained showed that IL-6 (显示 IL6 抗体) expression in adipose tissue biopsies derived from animals with equine metabolic syndrome was enhanced while TNF-alpha levels of both groups were comparable.
Data indicate that tumor necrosis factor-alpha production is closely related to ovarian steroid actions.
These results indicate that in equine corpus luteum, cytokines TNF, IFNG (显示 IFNG 抗体) and FASL (显示 FASL 抗体) regulate nitric oxide activity, via eNOS (显示 NOS3 抗体) expression modulation.
These data show the presence of cytokines TNF and IFNG (显示 IFNG 抗体), and their receptors, in the equine corpus luteum and indicate their potential involvement in regulation of luteal function.
The contribution of bronchial epithelium to airway inflammation, with focus on mRNA and protein expression of IL-6 (显示 IL6 抗体), IL-10 (显示 IL10 抗体) and TNF-alpha, in horses with recurrent airway obstruction during exacerbation and in remission is reported.
TUNEL staining was positively correlated with TNF-a protein expression. Our findings suggest that apoptosis can be induced in the vocal fold epithelium after 120min of modal intensity phonation. In contrast, shorter durations of vibration exposure do not result in apoptosis signaling.
Inflammatory factors such as TNF-alpha can stimulate MMP-2 (显示 MMP2 抗体)/9 activity in corneal epithelium cells. This may be a potential manipulating mechanism of MMP expression in the pathogenesis of corneal diseases.
The JNK (显示 MAPK8 抗体) pathway plays an important role in mechanical ventilation-stimulated TNF-alpha expression in alveolar macrophages, but the injury-stimulated IL-8 (显示 IL8 抗体) expression may be regulated by other signaling pathways.
The TNFalpha-evoked Cl- current.
IL-1beta (显示 IL1B 抗体) and TNF-alpha expression increases significantly during acute lung injury. Ambroxol combined with low-dose heparin inhibits teh release of IL-1beta (显示 IL1B 抗体) and TNF-alpha.
Hypercapnia increased expression of TNFa and decreased expression of NFKB in acute lung injury models.
In the early stages of myocardial ischemia, bone marrow stem cells are mobilized and home to ischemic myocardium with a concomitant increase in expression of cytokines VEGF (显示 VEGFA 抗体) and TNFalpha.
Ammonium perchlorate can increase gene expressions of types I, III collagens, TGF-beta(1 (显示 TGFB1 抗体)) and TNF-alpha in lung of rabbits.
TNFalpha may either be directly or indirectly involved in vascular damage following an embolic stroke. Moreover, TNFalpha may mediate some of the detrimental effects of tPA (显示 PLAT 抗体) on the vascular compartment
Data indicate that three single-nucleotide polymorphisms were identified in tumor necrosis factor-alpha (TNF-alpha) gene.
Macrophage- and neutrophil-derived TNF-alpha instructs skin langerhans cells to prime antiviral immune responses.
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
, TNF, macrophage-derived
, TNF, monocyte-derived
, tumor necrosis factor ligand superfamily member 2
, tumor necrosis factor-alpha
, tumor necrosis factor (TNF superfamily, member 2)
, tumor necrosis factor alpha
, tumor necrosis factor
, tumor-necrosis factor
, tumour necrosis factor
, TNF alpha
, ATP-binding cassette, sub-family F (GCN20), member 1
, tumour necrosis factor alpha
, tumor necrosis factor, alpha
, Tumor necrosis factor ligand superfamily member 2
, TNF-alpha 1