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Neuregulin 2 产品

(Neuregulin 2 (NRG2))
This gene encodes a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcript variants encoding distinct isoforms have been described. [provided by RefSeq, May 2010].

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Featured Neuregulin 2 Categories

Neuregulin 2 抗体

High quality antibodies with extensive validation data.

Neuregulin 2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Neuregulin 2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Neuregulin 2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse, Rat
Application WB, IHC, IF
Validations
  • (4)
Cat. No. ABIN7074804
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (3)
Cat. No. ABIN564118
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7164305
Quantity 100 μg
Datasheet Datasheet

Recommended Neuregulin 2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958087
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958088
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Competition ELISA
Validations
Cat. No. ABIN2112779
Quantity 96 tests
Datasheet Datasheet

Recommended Neuregulin 2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1313024
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3084550
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3084549
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Neuregulin 2 Products

Frogne, Benjaminsen, Sonne-Hansen, Sorensen, Nexo, Laenkholm, Rasmussen, Riese, de Cremoux, Stenvang, Lykkesfeldt: "Activation of ErbB3, EGFR and Erk is essential for growth of human breast cancer cell lines with acquired resistance to fulvestrant." in: Breast cancer research and treatment, Vol. 114, Issue 2, pp. 263-75, (2009) (PubMed).

Yamada, Ichino, Nishii, Sawada, Higashiyama, Ishiguro, Nagatsu: "Characterization of the human NTAK gene structure and distribution of the isoforms for rat NTAK mRNA." in: Gene, Vol. 255, Issue 1, pp. 15-24, (2000) (PubMed).

Ring, Chang, Guilbot, Brice, LeGuern, Francke: "The human neuregulin-2 (NRG2) gene: cloning, mapping and evaluation as a candidate for the autosomal recessive form of Charcot-Marie-Tooth disease linked to 5q." in: Human genetics, Vol. 104, Issue 4, pp. 326-32, (1999) (PubMed).

Higashiyama, Horikawa, Yamada, Ichino, Nakano, Nakagawa, Miyagawa, Matsushita, Nagatsu, Taniguchi, Ishiguro: "A novel brain-derived member of the epidermal growth factor family that interacts with ErbB3 and ErbB4." in: Journal of biochemistry, Vol. 122, Issue 3, pp. 675-80, (1998) (PubMed).

Carraway, Weber, Unger, Ledesma, Yu, Gassmann, Lai: "Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases." in: Nature, Vol. 387, Issue 6632, pp. 512-6, (1997) (PubMed).

Busfield, Michnick, Chickering, Revett, Ma, Woolf, Comrack, Dussault, Woolf, Goodearl, Gearing: "Characterization of a neuregulin-related gene, Don-1, that is highly expressed in restricted regions of the cerebellum and hippocampus." in: Molecular and cellular biology, Vol. 17, Issue 7, pp. 4007-14, (1997) (PubMed).

Synonyms and alternative names related to Neuregulin 2

neuregulin 2 (NRG2), neuregulin 2 (Nrg2), Don1, DON1, HRG2, NRG2, NTAK, Ntak, NTAK_alpha2a

Protein level used designations for Neuregulin 2

  • neuregulin 2
  • pro-NRG2
  • pro-neuregulin-2, membrane-bound isoform
  • divergent of neuregulin-1
  • neural- and thymus-derived activator for ErbB kinases
  • NTAK alpha1
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